| Host: | HEK293 |
| Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human IL-7 receptor (CD127)-protein was developed from hek293. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
| Storage Instruction: | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Immunoreactivity: | Recombinant Human IL-7 receptor alpha (CD127) Activity was determined by its binding ability of biotinylated mouse TSLP in a functional ELISA. NA |
| Gene Symbol: | IL7R |
| Gene ID: | 3575 |
| Uniprot ID: | IL7RA_HUMAN |
| Immunogen Region: | ECD |
| Immunogen: | Optimized DNA sequence encoding extracellular domain of Human IL-7 receptor alpha including a C-terminal His tag was expressed in HEK293 cells. NA |
| Post Translational Modifications | N-glycosylated IL-7Ralpha binds IL7 300-fold more tightly than the unglycosylated form. |
| Function | Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP). |
| Protein Name | Interleukin-7 Receptor Subunit AlphaIl-7 Receptor Subunit AlphaIl-7r Subunit AlphaIl-7r-AlphaIl-7raCdw127Cd Antigen Cd127 |
| Database Links | Reactome: R-HSA-1266695Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 3: Cell MembraneIsoform 4: Secreted |
| Alternative Protein Names | Interleukin-7 Receptor Subunit Alpha proteinIl-7 Receptor Subunit Alpha proteinIl-7r Subunit Alpha proteinIl-7r-Alpha proteinIl-7ra proteinCdw127 proteinCd Antigen Cd127 proteinIL7R protein |
Information sourced from Uniprot.org
