Human IL-13RA1/CD213a1 protein (Recombinant) (C-hFc&His) (STJP001106)

Human IL-13RA1/CD213a1 protein (Recombinant) (C-hFc&His) (STJP001106)

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STJP001106
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Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation: Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: < 0.1 EU/Mu g of the protein by LAL method.
Gene Symbol: IL13RA1
Gene ID: 3597
Uniprot ID: I13R1_HUMAN
Immunogen: Recombinant Human IL-13RA1/CD213a1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met 1-Thr 343) of human IL13RA1 (Accession #NP_001551.1) fused with an Fc, 6×His tag at the C-terminus.
Immunogen Sequence: MEWPARLCGLWALLLCAGGG GGGGGAAPTETQPPVTNLSV SVENLCTVIWTWNPPEGASS NCSLWYFSHFGDKQDKKIAP ETRRSIEVPLNERICLQVGS QCSTNESEKPSILVEKCISP PEGDPESAVTELQCIWHNLS YMKCSWLPGRNTSPDTNYTL YYWHRSLEKIHQCENIFREG QYFGCSFDLTKVKDSSFEQH SVQIMVKDNAGKIKPSFNIV PLTSRVKPDPPHIKNLSFH
Tissue Specificity Ubiquitous. Highest levels in heart, liver, skeletal muscle and ovary.lowest levels in brain, lung and kidney. Also found in B-cells, T-cells and endothelial cells.
Function Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.
Protein Name Interleukin-13 Receptor Subunit Alpha-1
Il-13 Receptor Subunit Alpha-1
Il-13r Subunit Alpha-1
Il-13r-Alpha-1
Il-13ra1
Cancer/Testis Antigen 19
Ct19
Cd Antigen Cd213a1
Database Links Reactome: R-HSA-6785807
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Interleukin-13 Receptor Subunit Alpha-1 protein
Il-13 Receptor Subunit Alpha-1 protein
Il-13r Subunit Alpha-1 protein
Il-13r-Alpha-1 protein
Il-13ra1 protein
Cancer/Testis Antigen 19 protein
Ct19 protein
Cd Antigen Cd213a1 protein
IL13RA1 protein
IL13R protein
IL13RA protein

Information sourced from Uniprot.org

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