Name: Human IFT57 protein (Recombinant) (N-His-SUMO & C-Strep) (STJP007421)
SKU: STJP007421
Availability: InStock

Human IFT57 protein (Recombinant) (N-His-SUMO & C-Strep) (STJP007421)

SKU:

STJP007421

£328.50 - £1,437.50

Free Shipping

Host:	E. coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Recombinant-Human IFT57-N-His-SUMO & C-Strep protein was developed from e. coli and has a target region of N-His-SUMO & C-Strep. For use in research applications.

Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway. Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator.however the relevance of such function remains unclear.
Protein Name	Intraflagellar Transport Protein 57 Homolog Dermal Papilla-Derived Protein 8 Estrogen-Related Receptor Beta-Like Protein 1 Hip1-Interacting Protein Mhs4r2
Database Links	Reactome: R-HSA-5610787 Reactome: R-HSA-5620924
Cellular Localisation	Cell Projection Cilium Cytoplasm Cytoskeleton Cilium Basal Body Concentrates Within The Inner Segment Of Cilia
Alternative Protein Names	Intraflagellar Transport Protein 57 Homolog protein Dermal Papilla-Derived Protein 8 protein Estrogen-Related Receptor Beta-Like Protein 1 protein Hip1-Interacting Protein protein Mhs4r2 protein IFT57 protein DERP8 protein ESRRBL1 protein HIPPI protein

Information sourced from Uniprot.org

Model	Name	Host
STJP008122	Human PICK1 protein (Recombinant) (N-His-SUMO & C-Strep) (STJP008122)	E. coli
STJP008188	Human NDUFA13 protein (Recombinant) (N-His-SUMO & C-Strep) (STJP008188)	E. coli
STJP009696	Human MYCBP protein (Recombinant) (N-His-SUMO & C-Strep) (STJP009696)	E. coli
STJP007957	Human TCF12 protein (Recombinant) (N-His-SUMO & C-Strep) (STJP007957)	E. coli
STJP007730	Human FHL2 protein (Recombinant) (N-His-SUMO & C-Strep) (STJP007730)	E. coli

Human IFT57 protein (Recombinant) (N-His-SUMO & C-Strep) (STJP007421)

General Information