Human ID1 protein (Recombinant) (His-Tag) (STJP018153)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human ID1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ID1 |
| Gene ID | 3397 |
| Uniprot ID | ID1_HUMAN |
| Accession Number | NP_002156 |
| Immunogen | Human |
| Immunogen Region | 1-155aa |
| Immunogen Sequence |
Additional Info
| Function | Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-BMAL1 heterodimer. |
| Protein Name | Dna-Binding Protein Inhibitor Id-1Class B Basic Helix-Loop-Helix Protein 24Bhlhb24Inhibitor Of Dna Binding 1Inhibitor Of Differentiation 1 |
| Database Links | Reactome: R-HSA-2559585Reactome: R-HSA-9031628Reactome: R-HSA-9856649 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Protein Names | Dna-Binding Protein Inhibitor Id-1 proteinClass B Basic Helix-Loop-Helix Protein 24 proteinBhlhb24 proteinInhibitor Of Dna Binding 1 proteinInhibitor Of Differentiation 1 proteinID1 proteinBHLHB24 proteinID protein |
Information sourced from Uniprot.org