Human IBSP protein (Recombinant-Active) (C-10*His) (STJP011921)

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STJP011921-100
€691.88
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human IBSP-C-10*His protein was developed from mammalian cells and has a target region of C-10*His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: IBSP
Gene ID: 3381
Uniprot ID: SIAL_HUMAN
Immunogen Region: Phe17-Gln317
Immunogen: Homo sapiens (Human)
Post Translational Modifications N-glycosylated.glycans consist of sialylated and core-fucosylated bi-, tri- and tetraantennary chains. O-glycosylated at eight sites.mucin-type glycans contain Gal, GlcNAc, GalNAc and terminal NeuAc.
Function Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes adhesion and migration of various cells via the alpha-V/beta-3 integrin receptor (ITGAV:ITGB3).
Protein Name Integrin-Binding Sialoprotein
Bone Sialoprotein 2
Bone Sialoprotein Ii
Bsp Ii
Cell-Binding Sialoprotein
Database Links Reactome: R-HSA-216083
Reactome: R-HSA-3000178
Cellular Localisation Secreted
Alternative Protein Names Integrin-Binding Sialoprotein
Bone Sialoprotein 2 protein
Bone Sialoprotein Ii protein
Bsp Ii protein
Cell-Binding Sialoprotein
IBSP protein
BNSP protein

Information sourced from Uniprot.org

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