Human HPR protein (Recombinant) (His-Tag) (STJP018680)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human HPR-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH8.5) containing 20% Glycerol, 1mM DTT, 0.15M NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HPR |
| Gene ID | 3250 |
| Uniprot ID | HPTR_HUMAN |
| Accession Number | NP_066275 |
| Immunogen | Human |
| Immunogen Region | 20-348aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | In adult liver the amount of HPR mRNA is at the lower limit of detection, therefore the extent of its expression is at most less than 1000-fold that of the HP1F gene. No HPR mRNA can be detected in fetal liver. Expressed in Hep-G2 and leukemia MOLT-4 cell lines. |
| Function | Primate-specific plasma protein associated with apolipoprotein L-I (apoL-I)-containing high-density lipoprotein (HDL). This HDL particle, termed trypanosome lytic factor-1 (TLF-1), mediates human innate immune protection against many species of African trypanosomes. Binds hemoglobin with high affinity and may contribute to the clearance of cell-free hemoglobin to allow hepatic recycling of heme iron. |
| Protein Name | Haptoglobin-Related Protein |
| Database Links | Reactome: R-HSA-2168880 |
| Cellular Localisation | SecretedSecreted Into Blood Plasma And Associated With Subtypes Of High Density Lipoproteins (Hdl) |
| Alternative Protein Names | Haptoglobin-Related Protein proteinHPR protein |
Information sourced from Uniprot.org