Human HMGN1 protein (Recombinant) (N-His) (STJP003704)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human HMGN1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | HMGN1 |
| Gene ID | 3150 |
| Uniprot ID | HMGN1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Lys14-Asp100 |
Additional Info
| Function | Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation. Inhibits the phosphorylation of nucleosomal histones H3 and H2A by RPS6KA5/MSK1 and RPS6KA3/RSK2. |
| Protein Name | Non-Histone Chromosomal Protein Hmg-14High Mobility Group Nucleosome-Binding Domain-Containing Protein 1 |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmCytoplasmic Enrichment Upon PhosphorylationThe Rna Edited Version Localizes To The Nucleus |
| Alternative Protein Names | Non-Histone Chromosomal Protein Hmg-14 proteinHigh Mobility Group Nucleosome-Binding Domain-Containing Protein 1 proteinHMGN1 proteinHMG14 protein |
Information sourced from Uniprot.org