| Short Description : | Recombinant-Active-Human HHIP-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications: | ELISA/WB |
| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity: | Measured by its ability to inhibit Sonic Hedgehog (Shh) induction of alkaline phosphatase production in mouse embryonic fibroblast cells (C3H10T1/2). Recombinant human HHIP inhibits a constant dose of 20 ng/mL of recombinant human Sonic Hedgehog/Shh |
| Gene Symbol: | HHIP |
| Gene ID: | 64399 |
| Uniprot ID: | HHIP_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Phe18-Asp670 |
| Function | Modulates hedgehog signaling in several cell types including brain and lung through direct interaction with members of the hedgehog family. |
| Protein Name | Hedgehog-Interacting ProteinHhipHip |
| Database Links | Reactome: R-HSA-5632681 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinSecretedThe Last 22 C-Terminal Amino Acids May Participate In Cell Membrane AttachmentIsoform 2: Cytoplasm |
| Alternative Protein Names | Hedgehog-Interacting Protein proteinHhip proteinHip proteinHHIP proteinHIP proteinUNQ5825 proteinPRO19644 protein |
Information sourced from Uniprot.org
