• Human Guanylyl cyclase C/GUCY2C protein (Recombinant) (C-His&Avi) (STJP001422)
  • Human Guanylyl cyclase C/GUCY2C protein (Recombinant) (C-His&Avi) (STJP001422)
  • Human Guanylyl cyclase C/GUCY2C protein (Recombinant) (C-His&Avi) (STJP001422)
  • Human Guanylyl cyclase C/GUCY2C protein (Recombinant) (C-His&Avi) (STJP001422)

Human Guanylyl cyclase C/GUCY2C protein (Recombinant) (C-His&Avi) (STJP001422)

SKU:
STJP001422

£76.50 - £231.50
Current Stock:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human Guanylyl cyclase C/GUCY2C-C-His&Avi protein was developed from hek293 cells and has a target region of C-His&Avi. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Endotoxin: Please contact us for more information.
Immunoreactivity: Measured by its binding ability in a functional ELISA. Immobilized Human GUCY2C at 1 Mu g/mL (100 Mu L/well) can bind GUCY2C Rabbit pAb with a linear range of 1-144 ng/mL.
Gene Symbol: GUCY2C
Gene ID: 2984
Uniprot ID: GUC2C_HUMAN
Immunogen: Recombinant Human Guanylyl cyclase C/GUCY2C Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ser24-Gln430) of human GUCY2C/Guanylyl cyclase (Accession #NP_004954.2) fused with a 6×His, Avi tag at t
Function Guanylyl cyclase that catalyzes synthesis of cyclic GMP (cGMP) from GTP. Receptor for the E.coli heat-stable enterotoxin.E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GUCY2C. Also activated by the endogenous peptides guanylin and uroguanylin.
Protein Name Guanylyl Cyclase C
Gc-C
Heat-Stable Enterotoxin Receptor
Sta Receptor
Hstar
Intestinal Guanylate Cyclase
Database Links Reactome: R-HSA-8935690
Reactome: R-HSA-8942233
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Endoplasmic Reticulum Membrane
The 145 Kda Plasma Membrane Form Of Gucy2c Contains Sialic Acid And Galactose Residues
While A Differencially Glycosylated 130 Kda Form Is A High Mannose Form That Is Resident In The Endoplasmic Reticulum And May Serve As The Precursor For The Cell Surface Form
Alternative Protein Names Guanylyl Cyclase C protein
Gc-C protein
Heat-Stable Enterotoxin Receptor protein
Sta Receptor protein
Hstar protein
Intestinal Guanylate Cyclase protein
GUCY2C protein
GUC2C protein
STAR protein

Information sourced from Uniprot.org

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