Human GRK6 protein (Recombinant) (N-His) (STJP004739)

SKU:
STJP004739
£208.50 - £1,163.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Short Description :Recombinant-Human GRK6-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:GRK6
Gene ID:2870
Uniprot ID:GRK6_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Phe186-Phe448
Post Translational Modifications It is uncertain whether palmitoylation is on Cys-561 and/or Cys-562 and/or Cys-565.
Function Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro).
Protein Name G Protein-Coupled Receptor Kinase 6
G Protein-Coupled Receptor Kinase Grk6
Database Links Reactome: R-HSA-418555
Cellular Localisation Membrane
Lipid-Anchor
Alternative Protein Names G Protein-Coupled Receptor Kinase 6 protein
G Protein-Coupled Receptor Kinase Grk6 protein
GRK6 protein
GPRK6 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP005172 Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172) E.coli SDS-PAGE/WB/ELISA/Immunogen
STJP004723 Human WAS protein (Recombinant) (N-His) (STJP004723) E.coli ELISA/Immunogen/SDS-PAGE/WB
STJP003416 Human CCNB2 protein (Recombinant) (N-His) (STJP003416) E.coli ELISA/Immunogen/SDS-PAGE/WB
STJP003432 Human SGPL1 protein (Recombinant) (N-His) (STJP003432) E.coli ELISA/Immunogen/SDS-PAGE/WB
STJP003434 Human H6PD protein (Recombinant) (N-His) (STJP003434) E.coli ELISA/Immunogen/SDS-PAGE/WB

Related Products

!