Human GPRC5A protein (Recombinant) (N-GST) (STJP006408)

SKU:
STJP006408
£328.50 - £1,437.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human GPRC5A-N-GST protein was developed from e. coli and has a target region of N-GST. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: GPRC5A
Gene ID: 9052
Uniprot ID: RAI3_HUMAN
Immunogen Region: Thr269-Ser357
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylated in two conserved double-tyrosine motifs, Tyr-317/Tyr-320 and Tyr-347/Tyr-350, by EGFR.leading to inactivation of the tumor suppressive function of GPRC5A in lung cancer cells. Tyr-317 and Tyr-320 are the preferred residues responsible for EGFR-mediated GPRC5A phosphorylation.
Function Orphan receptor. Could be involved in modulating differentiation and maintaining homeostasis of epithelial cells. This retinoic acid-inducible GPCR provide evidence for a possible interaction between retinoid and G-protein signaling pathways. Functions as a negative modulator of EGFR signaling. May act as a lung tumor suppressor.
Protein Name Retinoic Acid-Induced Protein 3
G-Protein Coupled Receptor Family C Group 5 Member A
Phorbol Ester Induced Gene 1
Peig-1
Retinoic Acid-Induced Gene 1 Protein
Raig-1
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cytoplasmic Vesicle Membrane
Localized In Perinuclear Vesicles
Probably Golgi-Associated Vesicles
Alternative Protein Names Retinoic Acid-Induced Protein 3 protein
G-Protein Coupled Receptor Family C Group 5 Member A protein
Phorbol Ester Induced Gene 1 protein
Peig-1 protein
Retinoic Acid-Induced Gene 1 Protein protein
Raig-1 protein
GPRC5A protein
GPCR5A protein
RAI3 protein
RAIG1 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP003503 Human AGT protein (Recombinant) (N-GST) (STJP003503) E. coli
STJP003471 Human F8 protein (Recombinant) (N-GST) (STJP003471) E. coli
STJP003444 Human BAG3 protein (Recombinant) (N-GST) (STJP003444) E. coli
STJP003829 Human NR3C2 protein (Recombinant) (N-GST) (STJP003829) E. coli
STJP003877 Human CD63 protein (Recombinant) (N-GST) (STJP003877) E. coli

Related Products

!