Name: Human GPRC5A protein (Recombinant) (N-GST) (STJP006408)
SKU: STJP006408
Availability: InStock

Human GPRC5A protein (Recombinant) (N-GST) (STJP006408)

SKU:

STJP006408

£208.50 - £1,163.50

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Short Description :	Recombinant-Human GPRC5A-N-GST protein was developed from e.coli for the region N-GST. For use in research applications.
Applications:	ELISA/Immunogen/SDS-PAGE/WB
Host:	E.coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range:	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Post Translational Modifications	Phosphorylated in two conserved double-tyrosine motifs, Tyr-317/Tyr-320 and Tyr-347/Tyr-350, by EGFR.leading to inactivation of the tumor suppressive function of GPRC5A in lung cancer cells. Tyr-317 and Tyr-320 are the preferred residues responsible for EGFR-mediated GPRC5A phosphorylation.
Function	Orphan receptor. Could be involved in modulating differentiation and maintaining homeostasis of epithelial cells. This retinoic acid-inducible GPCR provide evidence for a possible interaction between retinoid and G-protein signaling pathways. Functions as a negative modulator of EGFR signaling. May act as a lung tumor suppressor.
Protein Name	Retinoic Acid-Induced Protein 3 G-Protein Coupled Receptor Family C Group 5 Member A Phorbol Ester Induced Gene 1 Peig-1 Retinoic Acid-Induced Gene 1 Protein Raig-1
Database Links
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Cytoplasmic Vesicle Membrane Localized In Perinuclear Vesicles Probably Golgi-Associated Vesicles
Alternative Protein Names	Retinoic Acid-Induced Protein 3 protein G-Protein Coupled Receptor Family C Group 5 Member A protein Phorbol Ester Induced Gene 1 protein Peig-1 protein Retinoic Acid-Induced Gene 1 Protein protein Raig-1 protein GPRC5A protein GPCR5A protein RAI3 protein RAIG1 protein

Information sourced from Uniprot.org

Human GPRC5A protein (Recombinant) (N-GST) (STJP006408)

General Information

Model	Name	Host	Application
STJP003265	Human AQP9 protein (Recombinant) (N-GST) (STJP003265)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP003636	Human SLPI protein (Recombinant) (N-GST) (STJP003636)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP003401	Human SNCG protein (Recombinant) (N-GST) (STJP003401)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP003768	Human LIPF protein (Recombinant) (N-GST) (STJP003768)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP003515	Human MYC protein (Recombinant) (N-GST) (STJP003515)	E.coli	ELISA/Immunogen/SDS-PAGE/WB