Human Glutathione Peroxidase 2/GPX2 (U40C) protein (Recombinant) (His-Tag) (STJP017449)

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STJP017449
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human Glutathione Peroxidase 2/GPX2 (U40C)-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 7.5) containing 40% Glycerol, 0.15M NaCl, 1mM DTT
Concentration: 0.25 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: GPX2
Gene ID: 2877
Uniprot ID: GPX2_HUMAN
Immunogen Region: 1-190aa
Accession Number: NP_002074
Immunogen: Human
Immunogen Sequence: MGSSHHHHHH SSGLVPRGSH MAFIAKSFYD LSAISLDGEK VDFNTFRGRA VLIENVASLC GTTTRDFTQL NELQCRFPRR LVVLGFPCNQ FGHQENCQNE EILNSLKYVR PGGGYQPTFT LVQKCEVNGQ NEHPVFAYLK DKLPYPYDDP FSLMTDPKLI IWSPVRRSDV AWNFEKFLIG PEGEPFRRYS RTFPTINIEP DIKRLLKVAI
Tissue Specificity Mostly in liver and gastrointestinal tract, not found in heart or kidney.
Function Catalyzes the reduction of hydroperoxides in a glutathione-dependent manner thus regulating cellular redox homeostasis. Can reduce small soluble hydroperoxides such as H2O2, cumene hydroperoxide and tert-butyl hydroperoxide, as well as several fatty acid-derived hydroperoxides. Cannot reduce phosphatidycholine hydroperoxide.
Protein Name Glutathione Peroxidase 2
Gpx-2
Gshpx-2
Gastrointestinal Glutathione Peroxidase
Glutathione Peroxidase-Gastrointestinal
Gpx-Gi
Gshpx-Gi
Glutathione Peroxidase-Related Protein 2
Gprp-2
Phospholipid Hydroperoxide Glutathione Peroxidase Gpx2
Database Links Reactome: R-HSA-2142688
Reactome: R-HSA-2142712
Reactome: R-HSA-2142770
Reactome: R-HSA-3299685
Reactome: R-HSA-5628897
Cellular Localisation Cytoplasm
Cytosol
Alternative Protein Names Glutathione Peroxidase 2 protein
Gpx-2 protein
Gshpx-2 protein
Gastrointestinal Glutathione Peroxidase protein
Glutathione Peroxidase-Gastrointestinal protein
Gpx-Gi protein
Gshpx-Gi protein
Glutathione Peroxidase-Related Protein 2 protein
Gprp-2 protein
Phospholipid Hydroperoxide Glutathione Peroxidase Gpx2 protein
GPX2 protein

Information sourced from Uniprot.org

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