Human FXYD5/Dysadherin protein (Recombinant) (His-Tag) (STJP018075)

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STJP018075
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Short Description :Recombinant-Human FXYD5/Dysadherin-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.5 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% Glycerol, 1mM DTT
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:FXYD5
Gene ID:53827
Uniprot ID:FXYD5_HUMAN
Accession Number:NP_001158077.1
Immunogen:Human
Immunogen Region:22-145aa
Immunogen Sequence:QTLKDTT SSSSADSTIM DIQVPTRAPD AVYTELQPTS PTPTWPADET PQPQTQTQQL EGTDGPLVTD PETHKSTKAA HPTDDTTTLS ERPSPSTDVQ TDPQTLKPSG FHEDDPFFYD EHTLRKR
Post Translational Modifications Glycosylated.
Function Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. May increase NKA activity by increasing the apparent affinity for Na(+). Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis.
Protein Name Fxyd Domain-Containing Ion Transport Regulator 5
Dysadherin
Database Links
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Basolateral Cell Membrane
In Kidneys Localizes To The Basolateral Membrane Of The Connecting Tubule
Alternative Protein Names Fxyd Domain-Containing Ion Transport Regulator 5 protein
Dysadherin protein
FXYD5 protein
DYSAD protein
IWU1 protein
HSPC113 protein
UNQ2561 protein
PRO6241 protein

Information sourced from Uniprot.org

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