Human Follistatin-like 1 protein (Recombinant) (His-Tag) (STJP018405)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP018405
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General Information

Short DescriptionRecombinant-Human Follistatin-like 1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration0.5 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% Glycerol, 1mM DTT
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolFSTL1
Gene ID11167
Uniprot IDFSTL1_HUMAN
Accession NumberNP_009016.1
ImmunogenHuman
Immunogen Region21-308aa
Immunogen SequenceEEELRSKSK ICANVFCGAG RECAVTEKGE PTCLCIEQCK PHKRPVCGSN GKTYLNHCEL HRDACLTGSK IQVDYDGHCK EKKSVSPSAS PVVCYQSNRD ELRRRIIQWL EAEIIPDGWF SKGSNYSEIL DKYFKNFDNG DSRLDSSEFL KFVEQNETAI NITTYPDQEN NKLLRGLCVD ALIELSDENA DWKLSFQEFL KCLNPS

Additional Info

Tissue Specificity Overexpressed in synovial tissues from rheumatoid arthritis.
Function Secreted glycoprotein that is involved in various physiological processes, such as angiogenesis, regulation of the immune response, cell proliferation and differentiation. Plays a role in the development of the central nervous system, skeletal system, lungs, and ureter. Promotes endothelial cell survival, migration and differentiation into network structures in an AKT-dependent manner. Also promotes survival of cardiac myocytes. Initiates various signaling cascades by activating different receptors on the cell surface such as DIP2A, TLR4 or BMP receptors.
Protein Name Follistatin-Related Protein 1
Follistatin-Like Protein 1
Database Links Reactome: R-HSA-201451
Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Cellular Localisation Secreted
Alternative Protein Names Follistatin-Related Protein 1 protein
Follistatin-Like Protein 1 protein
FSTL1 protein
FRP protein

Information sourced from Uniprot.org

Citations

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