Human Follistatin-like 1/FSTL1 protein (Recombinant) (No-Tag) (STJP003068)

SKU:
STJP003068
£123.50 - £426.50
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Host: E.coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation: Lyophilised from 0.22 Mu m filtered solution in PBS (pH 7.4). Normally 8% Trehalose is added as protectant before lyophilisation.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: <0.01 EU/Mu g
Gene Symbol: FSTL1
Gene ID: 11167
Uniprot ID: FSTL1_HUMAN
Immunogen Region: Glu21-Ile308
Immunogen: Recombinant Human Follistatin-like protein 1/FSTL1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu21-Ile308) of Human Follistatin-like protein 1/FSTL1 (Accession #NP_009016.1) fused with a His
Immunogen Sequence: MSDSEVNQEAKPEVKPEVKP ETHINLKVSDGSSEIFFKIK KTTPLRRLMEAFAKRQGKEM DSLRFLYDGIRIQADQTPED LDMEDNDIIEAHREQIGG
Tissue Specificity Overexpressed in synovial tissues from rheumatoid arthritis.
Function Secreted glycoprotein that is involved in various physiological processes, such as angiogenesis, regulation of the immune response, cell proliferation and differentiation. Plays a role in the development of the central nervous system, skeletal system, lungs, and ureter. Promotes endothelial cell survival, migration and differentiation into network structures in an AKT-dependent manner. Also promotes survival of cardiac myocytes. Initiates various signaling cascades by activating different receptors on the cell surface such as DIP2A, TLR4 or BMP receptors.
Protein Name Follistatin-Related Protein 1
Follistatin-Like Protein 1
Database Links Reactome: R-HSA-201451
Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Cellular Localisation Secreted
Alternative Protein Names Follistatin-Related Protein 1 protein
Follistatin-Like Protein 1 protein
FSTL1 protein
FRP protein

Information sourced from Uniprot.org