• Human Fc-gamma RI/CD64 protein (Recombinant) (C-His) (STJP001241)
  • Human Fc-gamma RI/CD64 protein (Recombinant) (C-His) (STJP001241)
  • Human Fc-gamma RI/CD64 protein (Recombinant) (C-His) (STJP001241)
  • Human Fc-gamma RI/CD64 protein (Recombinant) (C-His) (STJP001241)
  • Human Fc-gamma RI/CD64 protein (Recombinant) (C-His) (STJP001241)
  • Human Fc-gamma RI/CD64 protein (Recombinant) (C-His) (STJP001241)

Human Fc-gamma RI/CD64 protein (Recombinant) (C-His) (STJP001241)

SKU:
STJP001241

£89.50 - £274.50
Current Stock:
Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation: Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: < 0.1 EU/Mu g of the protein by LAL method.
Immunoreactivity: Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human FCGR1A, His Tag at 2 Mu g/mL (100 Mu L/well) can bind Rituximab with a linear range of 15.625-58.38 ng/mL.
Gene Symbol: FCGR1A
Gene ID: 2209
Uniprot ID: FCGR1_HUMAN
Immunogen: Recombinant Human Fc-gamma RI/CD64 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Pro288) of human Fc gamma RI/CD64 (Accession #NP_000557.1) fused with a 6×His tag at the C-terminus.
Immunogen Sequence: MWFLTTLLLWVPVDGQVDTT KAVITLQPPWVSVFQEETVT LHCEVLHLPGSSSTQWFLNG TATQTSTPSYRITSASVNDS GEYRCQRGLSGRSDPIQLEI HRGWLLLQVSSRVFTEGEPL ALRCHAWKDKLVYNVLYYRN GKAFKFFHWNSNLTILKTNI SHNGTYHCSGMGKHRYTSAG ISVTVKELFPAPVLNASVTS PLLEGNLVTLSCETKLLLQR PGLQLYFSFYMGSKTLRGR
Post Translational Modifications Phosphorylated on serine residues.
Function High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Mediates IgG effector functions on monocytes triggering antibody-dependent cellular cytotoxicity (ADCC) of virus-infected cells.
Protein Name High Affinity Immunoglobulin Gamma Fc Receptor I
Igg Fc Receptor I
Fc-Gamma Ri
Fcri
Fc-Gamma Ria
Fcgammaria
Cd Antigen Cd64
Database Links Reactome: R-HSA-1236978
Reactome: R-HSA-198933
Reactome: R-HSA-2029481
Reactome: R-HSA-2029482
Reactome: R-HSA-2029485
Reactome: R-HSA-877300
Reactome: R-HSA-9664323
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Stabilized At The Cell Membrane Through Interaction With Fcer1g
Alternative Protein Names High Affinity Immunoglobulin Gamma Fc Receptor I protein
Igg Fc Receptor I protein
Fc-Gamma Ri protein
Fcri protein
Fc-Gamma Ria protein
Fcgammaria protein
Cd Antigen Cd64 protein
FCGR1A protein
FCG1 protein
FCGR1 protein
IGFR1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance