Human FABP2/I-FABP protein (Recombinant) (His-Tag) (STJP016447)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human FABP2/I-FABP-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin | < 1 EU per 1ug of protein (determined by LAL method) |
Target Information
| Gene Symbol | FABP2 |
| Gene ID | 2169 |
| Uniprot ID | FABPI_HUMAN |
| Accession Number | NP_000125 |
| Immunogen | Human |
| Immunogen Region | 1-132aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MAFDSTWKVD RSENYDKFME KMGVNIVKRK LAAHDNLKLT ITQEGNKFTV KESSAFRNIE VVFELGVTFN YNLADGTELR GTWSLEGNKL IGKFKRTDNG NELNTVREII GDELVQTYVY EGVEAKRIFK KD |
Additional Info
| Tissue Specificity | Expressed in the small intestine and at much lower levels in the large intestine. Highest expression levels in the jejunum. |
| Function | FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor. |
| Protein Name | Fatty Acid-Binding Protein - IntestinalFatty Acid-Binding Protein 2Intestinal-Type Fatty Acid-Binding ProteinI-Fabp |
| Database Links | Reactome: R-HSA-163560 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Fatty Acid-Binding Protein - Intestinal proteinFatty Acid-Binding Protein 2 proteinIntestinal-Type Fatty Acid-Binding Protein proteinI-Fabp proteinFABP2 proteinFABPI protein |
Information sourced from Uniprot.org