| Host: |
HEK293 cells |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human Ephrin-A3/EFNA3-C-hFc & His protein was developed from hek293 cells and has a target region of C-hFc & His. For use in research applications. |
| Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity: |
1.Measured by its binding ability in a functional ELISA. Immobilized Mouse EPHA6 at 1 Mu g/mL (100 Mu L/well) can bind Human EphrinA3 with a linear range of 0.3-113.9 ng/mL.2.Measured by its binding ability in a functional ELISA.Immobilized Mouse EPH |
| Gene Symbol: |
EFNA3 |
| Gene ID: |
1944 |
| Uniprot ID: |
EFNA3_HUMAN |
| Immunogen Region: |
Met 1-Ser 213 |
| Immunogen: |
Recombinant Human Ephrin-A3/EFNA3 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met 1-Ser 213) of human Ephrin A3 (Accession #NP_004943.1) fused with an Fc, 6×His tag at the C-terminus. |
| Function | Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. |
| Protein Name | Ephrin-A3Efl-2Ehk1 LigandEhk1-LEph-Related Receptor Tyrosine Kinase Ligand 3Lerk-3 |
| Database Links | Reactome: R-HSA-2682334Reactome: R-HSA-3928663Reactome: R-HSA-3928665 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Protein Names | Ephrin-A3 proteinEfl-2 proteinEhk1 Ligand proteinEhk1-L proteinEph-Related Receptor Tyrosine Kinase Ligand 3 proteinLerk-3 proteinEFNA3 proteinEFL2 proteinEPLG3 proteinLERK3 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
