| Post Translational Modifications | Phosphorylated. |
| Function | Endosome-associated protein that plays a role in membrane receptor sorting, cytokinesis and ciliogenesis. Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1. Involved in the regulation of cytokinesis.the function may involve PTPN13 and GIT1. Plays a role in the formation of cilia. Involved in cargo protein localization, such as PKD2, at primary cilia. Involved in the presentation of the tumor necrosis factor (TNF) receptor TNFRSF1A on the cell surface, and hence in the modulation of the TNF-induced apoptosis. |
| Protein Name | Endosome-Associated-Trafficking Regulator 1Antigen Ny-Co-3Serologically Defined Colon Cancer Antigen 3 |
| Cellular Localisation | CytoplasmEarly EndosomeEndosomeRecycling EndosomeMidbodyCytoskeletonMicrotubule Organizing CenterCentrosomeCilium Basal BodyColocalizes In A Washc2-Dependent Manner With The Retromer Csc Complex At EndosomesDuring Cytokinesis Colocalized With Ptpn13 At The MidbodyColocalizes With Ift88 And Gamma-Tubulin At The Basal Body Of Primary CiliaColocalizes With Ift88 And Pericentrin At The Centrosome |
| Alternative Protein Names | Endosome-Associated-Trafficking Regulator 1 proteinAntigen Ny-Co-3 proteinSerologically Defined Colon Cancer Antigen 3 proteinENTR1 proteinSDCCAG3 protein |
Information sourced from Uniprot.org
