Human DSPG3 protein (Recombinant) (His-Tag) (STJP019537)

SPECIFICATIONS
HostHEK293 Cells
ImmunogenHuman
STJP019537
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General Information

Short DescriptionRecombinant-Human DSPG3-His-Tag protein was developed from hek293 cells and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE/Bioactivity
HostHEK293 Cells
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration0.5 mg/mL
FormulationLiquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Endotoxin< 1 EU per 1ug of protein (determined by LAL method)
ImmunoreactivityMeasured by the ability of the immobilized protein to support the adhesion of Saos‑2 human osteosarcoma cells. When cells are added to human DSPG3 1.25 ug/ml and human fibronectin 0.5 ug/ml coated plates. This effect is more to 60%.

Target Information

Gene SymbolEPYC
Gene ID1833
Uniprot IDEPYC_HUMAN
Accession NumberNP_004941.2
ImmunogenHuman
Immunogen Region20-322aa
Immunogen SequenceAPTLESINYD SETYDATLED LDNLYNYENI PVDKVEIEIA TVMPSGNREL LTPPPQPEKA QEEEEEEEST PRLIDGSSPQ EPEFTGVLGP HTNEDFPTCL LCTCISTTVY CDDHELDAIP PLPKNTAYFY SRFNRIKKIN KNDFASLSDL KRIDLTSNLI SEIDEDAFRK LPQLRELVLR DNKIRQLPEL PTTLTFIDIS NNRLGRKGIK QEAFKDMYDL HHLYLTDN

Additional Info

Tissue Specificity Cartilage, ligament, and placenta.
Post Translational Modifications The O-linked polysaccharides on Thr-60 and Ser-96 are probably the mucin type linked to GalNAc. There is one glycosaminoglycan chain, known to be dermatan sulfate, and it is probably the O-glycosylation at Ser-64.
Function May have a role in bone formation and also in establishing the ordered structure of cartilage through matrix organization.
Protein Name Epiphycan
Dermatan Sulfate Proteoglycan 3
Proteoglycan-Lb
Pg-Lb
Small Chondroitin/Dermatan Sulfate Proteoglycan
Database Links
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Protein Names Epiphycan protein
Dermatan Sulfate Proteoglycan 3 protein
Proteoglycan-Lb protein
Pg-Lb protein
Small Chondroitin/Dermatan Sulfate Proteoglycan protein
EPYC protein
DSPG3 protein
PGLB protein
SLRR3B protein

Information sourced from Uniprot.org

Citations

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