Human DKKL1 protein (Recombinant-Active) (C-10*His) (STJP012315)

SKU:
STJP012315-100
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human DKKL1-C-10*His protein was developed from mammalian cells and has a target region of C-10*His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: DKKL1
Gene ID: 27120
Uniprot ID: DKKL1_HUMAN
Immunogen Region: Ala31-Leu242
Immunogen: Homo sapiens (Human)
Post Translational Modifications N-glycosylated during spermatogenesis. Not N-glycosylated in mature sperm.
Function Involved in fertilization by facilitating sperm penetration of the zona pellucida. May promote spermatocyte apoptosis, thereby limiting sperm production. In adults, may reduce testosterone synthesis in Leydig cells. Is not essential either for development or fertility.
Protein Name Dickkopf-Like Protein 1
Cancer/Testis Antigen 34
Ct34
Protein Soggy-1
Sgy-1
Cellular Localisation Secreted
Cytoplasmic Vesicle
Secretory Vesicle
Acrosome
Localized Specifically To The Crescent Shaped Acrosome At The Apex Of The Sperm Head
Alternative Protein Names Dickkopf-Like Protein 1 protein
Cancer/Testis Antigen 34 protein
Ct34 protein
Protein Soggy-1 protein
Sgy-1 protein
DKKL1 protein
SGY1 protein
UNQ735 protein
PRO1429 protein

Information sourced from Uniprot.org