| Function | Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid. |
| Protein Name | Peroxisomal 2 -4-Dienoyl-Coa Reductase (3e-Enoyl-Coa-ProducingPdcr2 -4-Dienoyl-Coa Reductase 2Short Chain Dehydrogenase/Reductase Family 17c Member 1 |
| Database Links | Reactome: R-HSA-390247Reactome: R-HSA-9033241 |
| Cellular Localisation | Peroxisome |
| Alternative Protein Names | Peroxisomal 2 -4-Dienoyl-Coa Reductase (3e-Enoyl-Coa-Producing proteinPdcr protein2 -4-Dienoyl-Coa Reductase 2 proteinShort Chain Dehydrogenase/Reductase Family 17c Member 1 proteinDECR2 proteinPDCR proteinSDR17C1 protein |
Information sourced from Uniprot.org