Human DcR3/TNFRSF6B protein (Recombinant) (His-Tag) (STJP018516)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human DcR3/TNFRSF6B-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol 0.4M urea |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TNFRSF6B |
| Gene ID | 8771 |
| Uniprot ID | TNF6B_HUMAN |
| Accession Number | NP_003814.1 |
| Immunogen | Human |
| Immunogen Region | 30-300aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Detected in fetal lung, brain and liver. Detected in adult stomach, spinal cord, lymph node, trachea, spleen, colon and lung. Highly expressed in several primary tumors from colon, stomach, rectum, esophagus and in SW480 colon carcinoma cells. |
| Function | Decoy receptor that can neutralize the cytotoxic ligands TNFS14/LIGHT, TNFSF15 and TNFSF6/FASL. Protects against apoptosis. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 6bDecoy Receptor 3Dcr3Decoy Receptor For Fas LigandM68 |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member 6b proteinDecoy Receptor 3 proteinDcr3 proteinDecoy Receptor For Fas Ligand proteinM68 proteinTNFRSF6B proteinDCR3 proteinTR6 proteinUNQ186 proteinPRO212 protein |
Information sourced from Uniprot.org