Host: | HEK293 cells |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Formulation: | Lyophilised from a 0.22 Mu m filtered solution of 50mM Tris, 150mM NaCl, pH 8.0. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Determination Method: | < 0.1 EU/Mu g of the protein by LAL method. |
Immunoreactivity: | Measured by its ability to inhibit active Cathepsin L cleavage of a fluorogenic peptide substrate Z-LR-AMC. The IC50 value is<2.5 nM. |
Gene Symbol: | CST2 |
Gene ID: | 1470 |
Uniprot ID: | CYTT_HUMAN |
Immunogen Region: | Trp21-Ala141 |
Immunogen: | Recombinant Human Cystatin-SA/CST2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Trp21-Ala141) of human Cystatin SA/CST2 (Accession #NP_001313.1) fused with a 6×His tag at the C-terminus. |
Immunogen Sequence: | WSPQEEDRIIEGGIYDADLN DERVQRALHFVISEYNKATE DEYYRRLLRVLRAREQIVGG VNYFFDIEVGRTICTKSQPN LDTCAFHEQPELQKKQLCSF QIYEVPWEDRMSLVNSRCQE A |
Function | Thiol protease inhibitor. |
Protein Name | Cystatin-SaCystatin-2Cystatin-S5 |
Cellular Localisation | Secreted |
Alternative Protein Names | Cystatin-Sa proteinCystatin-2 proteinCystatin-S5 proteinCST2 protein |
Information sourced from Uniprot.org