Human CTDSPL protein (Recombinant) (His-Tag) (STJP017531)

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STJP017531
£134.50 - £738.50
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CTDSPL-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 40% Glycerol, 0.15M NaCl, 1mM DTT
Concentration: 0.5 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: CTDSPL
Gene ID: 10217
Uniprot ID: CTDSL_HUMAN
Immunogen Region: 82-265aa
Accession Number: NP_005799
Immunogen: Human
Immunogen Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMKYLLP EVTVLDYGKK CVVIDLDETL VHSSFKPISN ADFIVPVEID GTIHQVYVLK RPHVDEFLQR MGQLFECVLF TASLAKYADP VADLLDRWGV FRARLFRESC VFHRGNYVKD LSRLGRELSK VIIVDNSPAS YIFHPENAVP VQSWFDDMTD TELLDLIPFF EGLSREDDVY SMLHRLCNR
Tissue Specificity Expression is restricted to non-neuronal tissues.
Function Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation.
Protein Name Ctd Small Phosphatase-Like Protein
Ctdsp-Like
Carboxy-Terminal Domain Rna Polymerase Ii Polypeptide A Small Phosphatase 3
Nif-Like Protein
Nuclear Lim Interactor-Interacting Factor 1
Nli-Interacting Factor 1
Protein Ya22
Hya22
Rbsp3
Small C-Terminal Domain Phosphatase 3
Scp3
Small Ctd Phosphatase 3
Database Links
Cellular Localisation Nucleus
Alternative Protein Names Ctd Small Phosphatase-Like Protein protein
Ctdsp-Like protein
Carboxy-Terminal Domain Rna Polymerase Ii Polypeptide A Small Phosphatase 3 protein
Nif-Like Protein protein
Nuclear Lim Interactor-Interacting Factor 1 protein
Nli-Interacting Factor 1 protein
Protein Ya22 protein
Hya22 protein
Rbsp3 protein
Small C-Terminal Domain Phosphatase 3 protein
Scp3 protein
Small Ctd Phosphatase 3 protein
CTDSPL protein
C3orf8 protein
NIF1 protein
NIFL protein
SCP3 protein
YA22 protein

Information sourced from Uniprot.org

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