Human CTDSP2 protein (Recombinant) (N-His) (STJP010621)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CTDSP2-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | CTDSP2 |
| Gene ID | 10106 |
| Uniprot ID | CTDS2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Thr95-Pro271 |
Additional Info
| Function | Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas. |
| Protein Name | Carboxy-Terminal Domain Rna Polymerase Ii Polypeptide A Small Phosphatase 2Nuclear Lim Interactor-Interacting Factor 2Nli-Interacting Factor 2Protein Os-4Small C-Terminal Domain Phosphatase 2Small Ctd Phosphatase 2Scp2 |
| Database Links | Reactome: R-HSA-381038 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Carboxy-Terminal Domain Rna Polymerase Ii Polypeptide A Small Phosphatase 2 proteinNuclear Lim Interactor-Interacting Factor 2 proteinNli-Interacting Factor 2 proteinProtein Os-4 proteinSmall C-Terminal Domain Phosphatase 2 proteinSmall Ctd Phosphatase 2 proteinScp2 proteinCTDSP2 proteinNIF2 proteinOS4 proteinSCP2 protein |
Information sourced from Uniprot.org