Human CST7 protein (Recombinant-Active) (C-His) (STJP011749)

SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
STJP011749-100
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General Information

Short DescriptionRecombinant-Active-Human CST7-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
ApplicationsELISA/WB
HostMammalian Cells
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ConjugationUnconjugated
Dilution RangeReconstitute in sterile water for a stock solution.
FormulationLyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin<0.1 EU/Mu g of the protein by the LAL method.
ImmunoreactivityMeasured by its ability to inhibit active Cathepsin L cleavage of a fluorogenic peptide substrate Z-LR-AMC. The IC50 value is <6.0 nM, as measured under the described conditions.

Target Information

Gene SymbolCST7
Gene ID8530
Uniprot IDCYTF_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionGly20-His145

Additional Info

Function Inhibits papain and cathepsin L but with affinities lower than other cystatins. May play a role in immune regulation through inhibition of a unique target in the hematopoietic system.
Protein Name Cystatin-F
Cystatin-7
Cystatin-Like Metastasis-Associated Protein
Cmap
Leukocystatin
Database Links
Cellular Localisation Secreted
Cytoplasm
Alternative Protein Names Cystatin-F protein
Cystatin-7 protein
Cystatin-Like Metastasis-Associated Protein protein
Cmap protein
Leukocystatin protein
CST7 protein

Information sourced from Uniprot.org

Citations

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