| Short Description : | Recombinant-Active-Human CST4-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications: | ELISA/WB |
| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity: | Measured by its ability to inhibit active Cathepsin L cleavage of a fluorogenic peptide substrate Z-LR-AMC. The IC50 value approximately is 26.3 nM. |
| Gene Symbol: | CST4 |
| Gene ID: | 1472 |
| Uniprot ID: | CYTS_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Ser21-Ala141 |
| Post Translational Modifications | Phosphorylated at both its N- and C-terminal regions. |
| Function | This protein strongly inhibits papain and ficin, partially inhibits stem bromelain and bovine cathepsin C, but does not inhibit porcine cathepsin B or clostripain. Papain is inhibited non-competitively. |
| Protein Name | Cystatin-SCystatin-4Cystatin-Sa-IiiSalivary Acidic Protein 1 |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Cystatin-S proteinCystatin-4 proteinCystatin-Sa-Iii proteinSalivary Acidic Protein 1 proteinCST4 protein |
Information sourced from Uniprot.org
