Human CRYM protein (Recombinant) (N-His) (STJP008199)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CRYM-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | CRYM |
| Gene ID | 1428 |
| Uniprot ID | CRYM_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Lys314 |
Additional Info
| Function | Catalyzes the NAD(P)H-dependent reduction of imine double bonds of a number of cyclic ketimine substrates, including sulfur-containing cyclic ketimines. Under physiological conditions, it efficiently catalyzes delta(1)-piperideine-2-carboxylate (P2C) and delta(1)-pyrroline-2-carboxylate (Pyr2C) reduction, suggesting a central role in lysine and glutamate metabolism. Additional substrates are delta(2)-thiazoline-2-carboxylate (T2C), 3,4-dehydrothiomorpholine-3-carboxylate (AECK), and (R)-lanthionine ketimine (LK) that is reduced at very low rate compared to other substrates. Also catalyzes the NAD(P)H-dependent reduction of (S)-cystathionine ketimine (CysK). |
| Protein Name | Ketimine Reductase Mu-Crystallin1-Piperideine-2-Carboxylate/1-Pyrroline-2-Carboxylate ReductaseP2c/Pyr2c ReductaseNadp-Regulated Thyroid-Hormone-Binding Protein |
| Database Links | Reactome: R-HSA-71064 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Ketimine Reductase Mu-Crystallin protein1-Piperideine-2-Carboxylate/1-Pyrroline-2-Carboxylate Reductase proteinP2c/Pyr2c Reductase proteinNadp-Regulated Thyroid-Hormone-Binding Protein proteinCRYM proteinTHBP protein |
Information sourced from Uniprot.org