| Host: | E.coli |
| Applications: | SDS-PAGE/Denatured |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human CPSF4-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% Glycerol |
| Concentration: | 1 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CPSF4 |
| Gene ID: | 10898 |
| Uniprot ID: | CPSF4_HUMAN |
| Immunogen Region: | 1-244aa |
| Accession Number: | NP_001075028 |
| Immunogen: | Human |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMQEIIAS VDHIKFDLEI AVEQQLGAQP LPFPGMDKSG AAVCEFFLKA ACGKGGMCPF RHISGEKTVV CKHWLRGLCK KGDQCEFLHE YDMTKMPECY FYSKFGECSN KECPFLHIDP ESKIKDCPWY DRGFCKHGPL CRHRHTRRVI CVNYLVGFCP EGPSCKFMHP RFELPMGTTE QPPLPQQTQP PAKQRTPQVI GVMQSQNS |
| Function | Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U). |
| Protein Name | Cleavage And Polyadenylation Specificity Factor Subunit 4Cleavage And Polyadenylation Specificity Factor 30 Kda SubunitCpsf 30 Kda SubunitNs1 Effector Domain-Binding Protein 1Neb-1No Arches Homolog |
| Database Links | Reactome: R-HSA-159231Reactome: R-HSA-168315Reactome: R-HSA-6784531Reactome: R-HSA-72187Reactome: R-HSA-72203Reactome: R-HSA-73856Reactome: R-HSA-77595 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Cleavage And Polyadenylation Specificity Factor Subunit 4 proteinCleavage And Polyadenylation Specificity Factor 30 Kda Subunit proteinCpsf 30 Kda Subunit proteinNs1 Effector Domain-Binding Protein 1 proteinNeb-1 proteinNo Arches Homolog proteinCPSF4 proteinCPSF30 proteinNAR proteinNEB1 protein |
Information sourced from Uniprot.org