Human CPSF4 protein (Recombinant) (His-Tag) (STJP018130)

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STJP018130
£134.50 - £738.50
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Host: E.coli
Applications: SDS-PAGE/Denatured
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CPSF4-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% Glycerol
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: CPSF4
Gene ID: 10898
Uniprot ID: CPSF4_HUMAN
Immunogen Region: 1-244aa
Accession Number: NP_001075028
Immunogen: Human
Immunogen Sequence: MGSSHHHHHH SSGLVPRGSH MGSMQEIIAS VDHIKFDLEI AVEQQLGAQP LPFPGMDKSG AAVCEFFLKA ACGKGGMCPF RHISGEKTVV CKHWLRGLCK KGDQCEFLHE YDMTKMPECY FYSKFGECSN KECPFLHIDP ESKIKDCPWY DRGFCKHGPL CRHRHTRRVI CVNYLVGFCP EGPSCKFMHP RFELPMGTTE QPPLPQQTQP PAKQRTPQVI GVMQSQNS
Function Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
Protein Name Cleavage And Polyadenylation Specificity Factor Subunit 4
Cleavage And Polyadenylation Specificity Factor 30 Kda Subunit
Cpsf 30 Kda Subunit
Ns1 Effector Domain-Binding Protein 1
Neb-1
No Arches Homolog
Database Links Reactome: R-HSA-159231
Reactome: R-HSA-168315
Reactome: R-HSA-6784531
Reactome: R-HSA-72187
Reactome: R-HSA-72203
Reactome: R-HSA-73856
Reactome: R-HSA-77595
Cellular Localisation Nucleus
Alternative Protein Names Cleavage And Polyadenylation Specificity Factor Subunit 4 protein
Cleavage And Polyadenylation Specificity Factor 30 Kda Subunit protein
Cpsf 30 Kda Subunit protein
Ns1 Effector Domain-Binding Protein 1 protein
Neb-1 protein
No Arches Homolog protein
CPSF4 protein
CPSF30 protein
NAR protein
NEB1 protein

Information sourced from Uniprot.org

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