Human COLEC12 protein (Recombinant) (N-His) (STJP016129)

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STJP016129
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Short Description :Recombinant-Human COLEC12-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:Please contact us for further information.
Gene Symbol:COLEC12
Gene ID:81035
Uniprot ID:COL12_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Glu603-Leu742
Function Scavenger receptor that displays several functions associated with host defense. Promotes binding and phagocytosis of Gram-positive, Gram-negative bacteria and yeast. Mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. Binds to several carbohydrates including Gal-type ligands, D-galactose, L- and D-fucose, GalNAc, T and Tn antigens in a calcium-dependent manner and internalizes specifically GalNAc in nurse-like cells. Also binds to sialyl Lewis X or a trisaccharide and asialo-orosomucoid (ASOR). May also play a role in the clearance of amyloid-beta in Alzheimer disease.
Protein Name Collectin-12
Collectin Placenta Protein 1
Cl-P1
Hcl-P1
Nurse Cell Scavenger Receptor 2
Scavenger Receptor Class A Member 4
Scavenger Receptor With C-Type Lectin
Database Links Reactome: R-HSA-198933
Reactome: R-HSA-3000480
Cellular Localisation Membrane
Single-Pass Type Ii Membrane Protein
Forms Clusters On The Cell Surface
Alternative Protein Names Collectin-12 protein
Collectin Placenta Protein 1 protein
Cl-P1 protein
Hcl-P1 protein
Nurse Cell Scavenger Receptor 2 protein
Scavenger Receptor Class A Member 4 protein
Scavenger Receptor With C-Type Lectin protein
COLEC12 protein
CLP1 protein
NSR2 protein
SCARA4 protein
SRCL protein

Information sourced from Uniprot.org