| Host: | E.coli |
| Applications: | Enzyme Activity/SDS-PAGE |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human CKMT1A-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol |
| Concentration: | 1 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity: | Specific activity is > 50unit/mg, and is defined as the amount of enzyme that convert 1.0 umole of phosphate from phosphocreatine to ADP per minute at pH 7.5 at 37C. |
| Gene Symbol: | CKMT1A.CKMT1B |
| Gene ID: | 1159/548596 |
| Uniprot ID: | KCRU_HUMAN |
| Immunogen Region: | 40-417aa |
| Accession Number: | NP_001015001 |
| Immunogen: | Human |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMASERR RLYPPSAEYP DLRKHNNCMA SHLTPAVYAR LCDKTTPTGW TLDQCIQTGV DNPGHPFIKT VGMVAGDEET YEVFADLFDP VIQERHNGYD PRTMKHTTDL DASKIRSGYF DERYVLSSRV RTGRSIRGLS LPPACTRAER REVERVVVDA LSGLKGDLAG RYYRLSEMTE AEQQQLIDDH FLFDKPVSPL LTAAGMAR |
| Function | Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. |
| Protein Name | Creatine Kinase U-Type - MitochondrialAcidic-Type Mitochondrial Creatine KinaseMia-CkUbiquitous Mitochondrial Creatine KinaseU-Mtck |
| Database Links | Reactome: R-HSA-71288 |
| Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane ProteinIntermembrane Side |
| Alternative Protein Names | Creatine Kinase U-Type - Mitochondrial proteinAcidic-Type Mitochondrial Creatine Kinase proteinMia-Ck proteinUbiquitous Mitochondrial Creatine Kinase proteinU-Mtck proteinCKMT1A proteinCKMT.CKMT1B proteinCKMT protein |
Information sourced from Uniprot.org