Human CHSY1 protein (Recombinant) (N-His) (STJP009659)

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STJP009659
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Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CHSY1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CHSY1
Gene ID: 22856
Uniprot ID: CHSS1_HUMAN
Immunogen Region: Leu87-His304
Immunogen: Homo sapiens (Human)
Function Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling.
Protein Name Chondroitin Sulfate Synthase 1
Chondroitin Glucuronyltransferase 1
Chondroitin Synthase 1
Chsy-1
Glucuronosyl-N-Acetylgalactosaminyl-Proteoglycan 4-Beta-N-Acetylgalactosaminyltransferase 1
N-Acetylgalactosaminyl-Proteoglycan 3-Beta-Glucuronosyltransferase 1
N-Acetylgalactosaminyltransferase 1
Database Links Reactome: R-HSA-2022870
Reactome: R-HSA-3595177
Cellular Localisation Golgi Apparatus
Golgi Stack Membrane
Single-Pass Type Ii Membrane Protein
Secreted
Alternative Protein Names Chondroitin Sulfate Synthase 1 protein
Chondroitin Glucuronyltransferase 1 protein
Chondroitin Synthase 1 protein
Chsy-1 protein
Glucuronosyl-N-Acetylgalactosaminyl-Proteoglycan 4-Beta-N-Acetylgalactosaminyltransferase 1 protein
N-Acetylgalactosaminyl-Proteoglycan 3-Beta-Glucuronosyltransferase 1 protein
N-Acetylgalactosaminyltransferase 1 protein
CHSY1 protein
CHSY protein
CSS1 protein
KIAA0990 protein
UNQ756 protein
PRO1487 protein

Information sourced from Uniprot.org

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