Human CDK2AP2 protein (Recombinant) (C-His) (STJP013007)

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STJP013007-100
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Host: Mammalian Cells
Applications: ELISA/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CDK2AP2-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Conjugation: Unconjugated
Formulation: Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: < 1 EU/µg as determined by LAL test.
Gene Symbol: CDK2AP2
Gene ID: 10263
Uniprot ID: CDKA2_HUMAN
Immunogen Region: Met1-Thr126
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylated by MAPK1 and CDK2.
Function Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Inhibits cell cycle G1/S phase transition by repressing CDK2 expression and activation.represses CDK2 activation by inhibiting its interaction with cyclin E and A. Plays a role in regulating the self-renewal of embryonic stem cells (ESCs) and in maintaining cell survival during terminal differentiation of ESCs. Regulates microtubule organization of metaphase II oocytes.
Protein Name Cyclin-Dependent Kinase 2-Associated Protein 2
Cdk2-Associated Protein 2
Doc-1-Related Protein
Doc-1r
Database Links
Cellular Localisation Cytoplasm
Nucleus
Accumulates In Immature Oocytes In The Nucleus
During The First Meiotic Division
Accumulates In The Cytoplasm And Localizes In Dots In The Vicinity Of The Chromosomes In A Region Enriched In Microtubules
Alternative Protein Names Cyclin-Dependent Kinase 2-Associated Protein 2 protein
Cdk2-Associated Protein 2 protein
Doc-1-Related Protein protein
Doc-1r protein
CDK2AP2 protein
DOC1R protein

Information sourced from Uniprot.org

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