• Human CDH6/K-Cadherin protein (Recombinant) (C-His) (STJP001013)
  • Human CDH6/K-Cadherin protein (Recombinant) (C-His) (STJP001013)
  • Human CDH6/K-Cadherin protein (Recombinant) (C-His) (STJP001013)
  • Human CDH6/K-Cadherin protein (Recombinant) (C-His) (STJP001013)

Human CDH6/K-Cadherin protein (Recombinant) (C-His) (STJP001013)

SKU:
STJP001013

£72.50 - £224.50
Current Stock:
Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation: Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: < 0.1 EU/Mu g of the protein by LAL method.
Immunoreactivity: Measured by its binding ability in a functional ELISA. Immobilized Human CDH6 at 1 Mu g/mL (100 Mu L/well) can bind CDH6 Mouse mAb with a linear range of 0.05-6.31 ng/mL.
Gene Symbol: CDH6
Gene ID: 1004
Uniprot ID: CADH6_HUMAN
Immunogen: Recombinant Human CDH6/K-Cadherin Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Thr 19-Ala 615 ) of human K-Cadherin (Accession #NP_004923.1) fused with a 6×His tag at the C-terminus.
Immunogen Sequence: TLSTPLSKRTSGFPAKKRAL ELSGNSKNELNRSKRSWMWN QFFLLEEYTGSDYQYVGKLH SDQDRGDGSLKYILSGDGAG DLFIINENTGDIQATKRLDR EEKPVYILRAQAINRRTGRP VEPESEFIIKIHDINDNEPI FTKEVYTATVPEMSDVGTFV VQVTATDADDPTYGNSAKVV YSILQGQPYFSVESETGIIK TALLNMDRENREQYQVVIQA KDMGGQMGGLSGTTTVNIT
Tissue Specificity Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas.
Function Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells.cadherins may thus contribute to the sorting of heterogeneous cell types.
Protein Name Cadherin-6
Kidney Cadherin
K-Cadherin
Database Links Reactome: R-HSA-418990
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Cadherin-6 protein
Kidney Cadherin protein
K-Cadherin protein
CDH6 protein

Information sourced from Uniprot.org

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