| Host: |
HEK293 cells |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human CDH6/K-Cadherin-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
| Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation. |
| Immunoreactivity: |
Measured by its binding ability in a functional ELISA. Immobilized Human CDH6 at 1 Mu g/mL (100 Mu L/well) can bind CDH6 Mouse mAb with a linear range of 0.05-6.31 ng/mL. |
| Gene Symbol: |
CDH6 |
| Gene ID: |
1004 |
| Uniprot ID: |
CADH6_HUMAN |
| Immunogen: |
Recombinant Human CDH6/K-Cadherin Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Thr 19-Ala 615 ) of human K-Cadherin (Accession #NP_004923.1) fused with a 6×His tag at the C-terminus. |
| Tissue Specificity | Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas. |
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells.cadherins may thus contribute to the sorting of heterogeneous cell types. |
| Protein Name | Cadherin-6Kidney CadherinK-Cadherin |
| Database Links | Reactome: R-HSA-418990 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Cadherin-6 proteinKidney Cadherin proteinK-Cadherin proteinCDH6 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
