| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 0.1 EU/Mu g of the protein by LAL method. |
| Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilized Human CDH17 at 1 Mu g/mL (100 Mu L/well) can bind anti Human CDH17 antibody with a linear range of 0.01-20ng/mL. |
| Gene Symbol: | CDH17 |
| Gene ID: | 1015 |
| Uniprot ID: | CAD17_HUMAN |
| Immunogen: | Recombinant Human CDH17/LI-cadherin Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln23-Met787) of human Cadherin-17/LI-cadherin/CDH17 (Accession #NP_001138135.1) fused with a 6×His tag at the C |
| Immunogen Sequence: | QEGKFSGPLKPMTFSIYEGQ EPSQIIFQFKANPPAVTFEL TGETDNIFVIEREGLLYYNR ALDRETRSTHNLQVAALDAN GIIVEGPVPITIKVKDINDN RPTFLQSKYEGSVRQNSRPG KPFLYVNATDLDDPATPNGQ LYYQIVIQLPMINNVMYFQI NNKTGAISLTREGSQELNPA KNPSYNLVISVKDMGGQSEN SFSDTTSVDIIVTENIWKAP KPVEMVENSTDPHPIKITQ |
| Tissue Specificity | Expressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung, liver, brain, adrenal gland and skin. |
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells.cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport. |
| Protein Name | Cadherin-17Intestinal Peptide-Associated Transporter Hpt-1Liver-Intestine CadherinLi-Cadherin |
| Database Links | Reactome: R-HSA-418990 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Cadherin-17 proteinIntestinal Peptide-Associated Transporter Hpt-1 proteinLiver-Intestine Cadherin proteinLi-Cadherin proteinCDH17 protein |
Information sourced from Uniprot.org
