Host: |
HEK293 cells |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Formulation: |
Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Determination Method: |
< 0.1 EU/Mu g of the protein by LAL method. |
Immunoreactivity: |
Measured by its binding ability in a functional ELISA. Immobilized Human CDH17 at 1 Mu g/mL (100 Mu L/well) can bind anti Human CDH17 antibody with a linear range of 0.01-20ng/mL. |
Gene Symbol: |
CDH17 |
Gene ID: |
1015 |
Uniprot ID: |
CAD17_HUMAN |
Immunogen: |
Recombinant Human CDH17/LI-cadherin Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln23-Met787) of human Cadherin-17/LI-cadherin/CDH17 (Accession #NP_001138135.1) fused with a 6×His tag at the C |
Immunogen Sequence: |
QEGKFSGPLKPMTFSIYEGQ EPSQIIFQFKANPPAVTFEL TGETDNIFVIEREGLLYYNR ALDRETRSTHNLQVAALDAN GIIVEGPVPITIKVKDINDN RPTFLQSKYEGSVRQNSRPG KPFLYVNATDLDDPATPNGQ LYYQIVIQLPMINNVMYFQI NNKTGAISLTREGSQELNPA KNPSYNLVISVKDMGGQSEN SFSDTTSVDIIVTENIWKAP KPVEMVENSTDPHPIKITQ |
Tissue Specificity | Expressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung, liver, brain, adrenal gland and skin. |
Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells.cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport. |
Protein Name | Cadherin-17Intestinal Peptide-Associated Transporter Hpt-1Liver-Intestine CadherinLi-Cadherin |
Database Links | Reactome: R-HSA-418990 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative Protein Names | Cadherin-17 proteinIntestinal Peptide-Associated Transporter Hpt-1 proteinLiver-Intestine Cadherin proteinLi-Cadherin proteinCDH17 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance