Human CD336/NCR2 protein (Recombinant-Active) (C-His) (STJP011759)

SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
STJP011759-100
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General Information

Short DescriptionRecombinant-Active-Human CD336/NCR2-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
ApplicationsELISA/WB
HostMammalian Cells
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ConjugationUnconjugated
Dilution RangeReconstitute in sterile water for a stock solution.
FormulationLyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8ร‚ยฐC for one week. Store at-20 to-80ร‚ยฐC for twelve months from the date of receipt.
Endotoxin<0.1 EU/Mu g of the protein by the LAL method.
ImmunoreactivityMeasured by its binding ability in a functional ELISA. Recombinant human CD336/NCR2 binds recombinant human PDGFDD with an ED50 of 0.150-1.80 ร‚ยตg/mL.

Target Information

Gene SymbolNCR2
Gene ID9436
Uniprot IDNCTR2_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionGln22-Pro190

Additional Info

Function Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
Protein Name Natural Cytotoxicity Triggering Receptor 2
Lymphocyte Antigen 95 Homolog
Nk Cell-Activating Receptor
Natural Killer Cell P44-Related Protein
Nk-P44
Nkp44
Cd Antigen Cd336
Database Links Reactome: R-HSA-198933
Reactome: R-HSA-2172127
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Natural Cytotoxicity Triggering Receptor 2 protein
Lymphocyte Antigen 95 Homolog protein
Nk Cell-Activating Receptor protein
Natural Killer Cell P44-Related Protein protein
Nk-P44 protein
Nkp44 protein
Cd Antigen Cd336 protein
NCR2 protein
LY95 protein

Information sourced from Uniprot.org

Citations

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