Human CD336/NCR2 protein (Recombinant-Active) (C-His) (STJP011759)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Active-Human CD336/NCR2-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8รยฐC for one week. Store at-20 to-80รยฐC for twelve months from the date of receipt. |
| Endotoxin | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity | Measured by its binding ability in a functional ELISA. Recombinant human CD336/NCR2 binds recombinant human PDGFDD with an ED50 of 0.150-1.80 รยตg/mL. |
Target Information
| Gene Symbol | NCR2 |
| Gene ID | 9436 |
| Uniprot ID | NCTR2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gln22-Pro190 |
Additional Info
| Function | Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. |
| Protein Name | Natural Cytotoxicity Triggering Receptor 2Lymphocyte Antigen 95 HomologNk Cell-Activating ReceptorNatural Killer Cell P44-Related ProteinNk-P44Nkp44Cd Antigen Cd336 |
| Database Links | Reactome: R-HSA-198933Reactome: R-HSA-2172127 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Natural Cytotoxicity Triggering Receptor 2 proteinLymphocyte Antigen 95 Homolog proteinNk Cell-Activating Receptor proteinNatural Killer Cell P44-Related Protein proteinNk-P44 proteinNkp44 proteinCd Antigen Cd336 proteinNCR2 proteinLY95 protein |
Information sourced from Uniprot.org