Human CD307a/FCRL1 protein (Recombinant) (C-His) (STJP007126)

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STJP007126
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Short Description :Recombinant-Human CD307a/FCRL1-C-His protein was developed from mammalian cells for the region C-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:Mammalian Cells
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:FCRL1
Gene ID:115350
Uniprot ID:FCRL1_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Met1-Asn303
Post Translational Modifications Phosphorylated on tyrosines upon activation.
Function Type I transmembrane surface glycoprotein preferentially expressed by B-cells that regulates BCR-mediated signaling responses. Recruits ABL1 as the intracellular effector molecule to enhance B-cell activation. Also plays a negative role by suppressing ERK activation under homeostatic and BCR-stimulated conditions in a GRB2-dependent manner.
Protein Name Fc Receptor-Like Protein 1
Fcr-Like Protein 1
Fcrl1
Fc Receptor Homolog 1
Fcrh1
Ifgp Family Protein 1
Hifgp1
Immune Receptor Translocation-Associated Protein 5
Cd Antigen Cd307a
Database Links
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Fc Receptor-Like Protein 1 protein
Fcr-Like Protein 1 protein
Fcrl1 protein
Fc Receptor Homolog 1 protein
Fcrh1 protein
Ifgp Family Protein 1 protein
Hifgp1 protein
Immune Receptor Translocation-Associated Protein 5 protein
Cd Antigen Cd307a protein
FCRL1 protein
FCRH1 protein
IFGP1 protein
IRTA5 protein

Information sourced from Uniprot.org

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