Human CD300a protein (Recombinant) (C-Fc) (STJP007144)

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STJP007144
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD300a-C-Fc protein was developed from mammalian cells and has a target region of C-Fc. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CD300A
Gene ID: 11314
Uniprot ID: CLM8_HUMAN
Immunogen Region: Met1-Gln178
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylated on tyrosine. N-glycosylated.
Function Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6.
Protein Name Cmrf35-Like Molecule 8
Clm-8
Cd300 Antigen-Like Family Member A
Cmrf-35-H9
Cmrf35-H9
Cmrf35-H
Irc1/Irc2
Immunoglobulin Superfamily Member 12
Igsf12
Inhibitory Receptor Protein 60
Irp60
Nk Inhibitory Receptor
Cd Antigen Cd300a
Database Links Reactome: R-HSA-198933
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Cmrf35-Like Molecule 8 protein
Clm-8 protein
Cd300 Antigen-Like Family Member A protein
Cmrf-35-H9 protein
Cmrf35-H9 protein
Cmrf35-H protein
Irc1/Irc2 protein
Immunoglobulin Superfamily Member 12 protein
Igsf12 protein
Inhibitory Receptor Protein 60 protein
Irp60 protein
Nk Inhibitory Receptor protein
Cd Antigen Cd300a protein
CD300A protein
CMRF35H protein
IGSF12 protein
HSPC083 protein

Information sourced from Uniprot.org

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