Human CD273/PD-L2/PDCD1LG2 protein (Recombinant) (C-mFc) (STJP013565)

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STJP013565-100
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Short Description :Recombinant-Human CD273/PD-L2/PDCD1LG2-C-mFc protein was developed from mammalian cells and has a target region of C-mFc. For use in research applications.
Applications:ELISA/WB
Host:Mammalian Cells
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Unconjugated
Dilution Range:Reconstitute in sterile water for a stock solution.
Formulation:Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:< 1 EU/µg as determined by LAL test.
Gene Symbol:PDCD1LG2
Gene ID:80380
Uniprot ID:PD1L2_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Leu20-Pro219
Function Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
Protein Name Programmed Cell Death 1 Ligand 2
Pd-1 Ligand 2
Pd-L2
Pdcd1 Ligand 2
Programmed Death Ligand 2
Butyrophilin B7-Dc
B7-Dc
Cd Antigen Cd273
Database Links Reactome: R-HSA-389948
Cellular Localisation Isoform 3: Secreted
Isoform 2: Endomembrane System
Single-Pass Type I Membrane Protein
Isoform 1: Cell Membrane
Alternative Protein Names Programmed Cell Death 1 Ligand 2 protein
Pd-1 Ligand 2 protein
Pd-L2 protein
Pdcd1 Ligand 2 protein
Programmed Death Ligand 2 protein
Butyrophilin B7-Dc protein
B7-Dc protein
Cd Antigen Cd273 protein
PDCD1LG2 protein
B7DC protein
CD273 protein
PDCD1L2 protein
PDL2 protein

Information sourced from Uniprot.org

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