Human CD218a/IL18R1 protein (Recombinant) (C-Fc) (STJP007094)

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STJP007094
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD218a/IL18R1-C-Fc protein was developed from mammalian cells and has a target region of C-Fc. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: IL18R1
Gene ID: 8809
Uniprot ID: IL18R_HUMAN
Immunogen Region: Met1-Arg329
Immunogen: Homo sapiens (Human)
Post Translational Modifications N-glycosylated. N-linked glycosyl chains contribute to ligand recognition and intra-receptor interactions required for formation of an active ternary receptor complex.
Function Within the IL18 receptor complex, responsible for the binding of the pro-inflammatory cytokine IL18, but not IL1A nor IL1B. Involved in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells. Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3.
Protein Name Interleukin-18 Receptor 1
Il-18r-1
Il-18r1
Cd218 Antigen-Like Family Member A
Cdw218a
Il1 Receptor-Related Protein
Il-1rrp
Il1r-Rp
Interleukin-18 Receptor Alpha
Il-18r-Alpha
Il-18ralpha
Cd Antigen Cd218a
Database Links Reactome: R-HSA-9008059
Reactome: R-HSA-9012546
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Interleukin-18 Receptor 1 protein
Il-18r-1 protein
Il-18r1 protein
Cd218 Antigen-Like Family Member A protein
Cdw218a protein
Il1 Receptor-Related Protein protein
Il-1rrp protein
Il1r-Rp protein
Interleukin-18 Receptor Alpha protein
Il-18r-Alpha protein
Il-18ralpha protein
Cd Antigen Cd218a protein
IL18R1 protein
IL1RRP protein

Information sourced from Uniprot.org

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