Human CCL16/HCC-4 protein (Recombinant) (Tag free) (STJP014265)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CCL16/HCC-4-Tag free protein was developed from e.coli and has a target region of Tag free. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in 20mM PB, 150mM NaCl, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8ยฐC for one week. Store at-20 to-80ยฐC for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/ยตg as determined by LAL test. |
Target Information
| Gene Symbol | CCL16 |
| Gene ID | 6360 |
| Uniprot ID | CCL16_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gln24-Gln120 |
Additional Info
| Function | Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES. |
| Protein Name | C-C Motif Chemokine 16Chemokine Cc-4Hcc-4Chemokine LecIl-10-Inducible ChemokineLcc-1Liver-Expressed ChemokineLymphocyte And Monocyte ChemoattractantLmcMonotactin-1Mtn-1Ncc-4Small-Inducible Cytokine A16 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | C-C Motif Chemokine 16 proteinChemokine Cc-4 proteinHcc-4 proteinChemokine Lec proteinIl-10-Inducible Chemokine proteinLcc-1 proteinLiver-Expressed Chemokine proteinLymphocyte And Monocyte Chemoattractant proteinLmc proteinMonotactin-1 proteinMtn-1 proteinNcc-4 proteinSmall-Inducible Cytokine A16 proteinCCL16 proteinILINCK proteinNCC4 proteinSCYA16 protein |
Information sourced from Uniprot.org