Human CCL11/Eotaxin protein (Recombinant) (Tag free) (STJP014526)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CCL11/Eotaxin-Tag free protein was developed from e.coli and has a target region of Tag free. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in 20mM PB, 150mM NaCl, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | CCL11 |
| Gene ID | 6356 |
| Uniprot ID | CCL11_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gly24-Pro97 |
Additional Info
| Function | In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3. |
| Protein Name | EotaxinC-C Motif Chemokine 11Eosinophil Chemotactic ProteinSmall-Inducible Cytokine A11 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-6785807 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Eotaxin proteinC-C Motif Chemokine 11 proteinEosinophil Chemotactic Protein proteinSmall-Inducible Cytokine A11 proteinCCL11 proteinSCYA11 protein |
Information sourced from Uniprot.org