Human CAPN3 protein (Recombinant) (N-His) (STJP004295)

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STJP004295
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CAPN3-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CAPN3
Gene ID: 825
Uniprot ID: CAN3_HUMAN
Immunogen Region: Ile602-Ala821
Immunogen: Homo sapiens (Human)
Function Calcium-regulated non-lysosomal thiol-protease. Proteolytically cleaves CTBP1 at 'His-409'. Mediates, with UTP25, the proteasome-independent degradation of p53/TP53.
Protein Name Calpain-3
Calcium-Activated Neutral Proteinase 3
Canp 3
Calpain L3
Calpain P94
Muscle-Specific Calcium-Activated Neutral Protease 3
New Calpain 1
Ncl-1
Database Links Reactome: R-HSA-1474228
Cellular Localisation Cytoplasm
Nucleus
Nucleolus
Alternative Protein Names Calpain-3 protein
Calcium-Activated Neutral Proteinase 3 protein
Canp 3 protein
Calpain L3 protein
Calpain P94 protein
Muscle-Specific Calcium-Activated Neutral Protease 3 protein
New Calpain 1 protein
Ncl-1 protein
CAPN3 protein
CANP3 protein
CANPL3 protein
NCL1 protein

Information sourced from Uniprot.org