Human CAMLG protein (Recombinant) (N-His) (STJP004805)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CAMLG-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | CAMLG |
| Gene ID | 819 |
| Uniprot ID | CAMLG_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gly19-Glu184 |
Additional Info
| Function | Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1/WRB, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. Required for the stability of GET1. Stimulates calcium signaling in T cells through its involvement in elevation of intracellular calcium. Essential for the survival of peripheral follicular B cells. |
| Protein Name | Guided Entry Of Tail-Anchored Proteins Factor CamlgCalcium Signal-Modulating Cyclophilin Ligand |
| Database Links | Reactome: R-HSA-9609523 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | Guided Entry Of Tail-Anchored Proteins Factor Camlg proteinCalcium Signal-Modulating Cyclophilin Ligand proteinCAMLG proteinCAML proteinGET2 protein |
Information sourced from Uniprot.org