| Function | Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component. |
| Protein Name | C4b-Binding Protein Alpha ChainC4bpProline-Rich ProteinPrp |
| Database Links | Reactome: R-HSA-977606 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | C4b-Binding Protein Alpha Chain proteinC4bp proteinProline-Rich Protein proteinPrp proteinC4BPA proteinC4BP protein |
Information sourced from Uniprot.org