Name: Human BPHL protein (Recombinant) (His-Tag) (STJP017008)
SKU: STJP017008
Availability: InStock

Human BPHL protein (Recombinant) (His-Tag) (STJP017008)

SKU:

STJP017008

£134.50 - £738.50

Short Description :	Recombinant-Human BPHL-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:	SDS-PAGE
Host:	E.coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration:	0.5 mg/mL
Formulation:	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 1mM DTT, 50mM NaCl
Storage Instruction:	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol:	BPHL
Gene ID:	670
Uniprot ID:	BPHL_HUMAN
Accession Number:	NP_004323
Immunogen:	Human
Immunogen Region:	38-291aa
Immunogen Sequence:	MGSSHHHHHH SSGLVPRGSH MSVTSAKVAV NGVQLHYQQT GEGDHAVLLL PGMLGSGETD FGPQLKNLNK KLFTVVAWDP RGYGHSRPPD RDFPADFFER DAKDAVDLMK ALKFKKVSLL GWSDGGITAL IAAAKYPSYI HKMVIWGANA YVTDEDSMIY EGIRDVSKWS ERTRKPLEAL YGYDYFARTC EKWVDGIRQF KHLPDGNICR HLLPRVQCPA LIVHGEKD

Tissue Specificity	Expressed at high levels in liver and kidney and lower levels in heart, intestine and skeletal muscle.
Function	Specific alpha-amino acid ester serine hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol. Has homocysteine-thiolactonase activity (in vitro) and may play a significant role in the detoxification of homocysteine thiolactone in vivo. Catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir, converting them into their active forms (acyclovir and ganciclovir).
Protein Name	Serine Hydrolase Bphl Biphenyl Hydrolase-Like Protein Biphenyl Hydrolase-Related Protein Bph-Rp Breast Epithelial Mucin-Associated Antigen Mcnaa L-Homocysteine-Thiolactonase Bphl Valacyclovir Hydrolase Vacvase Valacyclovirase
Database Links	Reactome: R-HSA-211945
Cellular Localisation	Mitochondrion
Alternative Protein Names	Serine Hydrolase Bphl protein Biphenyl Hydrolase-Like Protein protein Biphenyl Hydrolase-Related Protein protein Bph-Rp protein Breast Epithelial Mucin-Associated Antigen protein Mcnaa protein L-Homocysteine-Thiolactonase Bphl protein Valacyclovir Hydrolase protein Vacvase protein Valacyclovirase protein BPHL protein MCNAA protein

Information sourced from Uniprot.org

Human BPHL protein (Recombinant) (His-Tag) (STJP017008)

General Information

Model	Name	Host	Application
STJP019170	Human FGB protein (Recombinant) (His-Tag) (STJP019170)	E.coli	SDS-PAGE
STJP019149	Human PYCR2 protein (Recombinant) (His-Tag) (STJP019149)	E.coli	SDS-PAGE
STJP019163	Human ALDH6A1 protein (Recombinant) (His-Tag) (STJP019163)	E.coli	SDS-PAGE
STJP019189	Human UBE2Q2 protein (Recombinant) (His-Tag) (STJP019189)	E.coli	SDS-PAGE
STJP019134	Human ETNK2 protein (Recombinant) (His-Tag) (STJP019134)	E.coli	SDS-PAGE