Human BCO2 protein (Recombinant) (N-His) (STJP008105)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human BCO2-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | BCO2 |
| Gene ID | 83875 |
| Uniprot ID | BCDO2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ser69-Ile579 |
Additional Info
| Function | Broad specificity mitochondrial dioxygenase that mediates the asymmetric oxidative cleavage of carotenoids. Cleaves carotenes (pure hydrocarbon carotenoids) such as all-trans-beta-carotene and lycopene as well as xanthophylls (oxygenated carotenoids) such as zeaxanthin, lutein and beta-cryptoxanthin at both the 9,10 and the 9',10' carbon-carbon double bond. Through its function in carotenoids metabolism regulates oxidative stress and the production of important signaling molecules. |
| Protein Name | Carotenoid-Cleaving Dioxygenase - MitochondrialB-Diox-IiBeta -Beta-Carotene 9' -10'-OxygenaseBeta-Carotene Dioxygenase 2 |
| Database Links | Reactome: R-HSA-975634 |
| Cellular Localisation | Mitochondrion |
| Alternative Protein Names | Carotenoid-Cleaving Dioxygenase - Mitochondrial proteinB-Diox-Ii proteinBeta -Beta-Carotene 9' -10'-Oxygenase proteinBeta-Carotene Dioxygenase 2 proteinBCO2 proteinBCDO2 protein |
Information sourced from Uniprot.org